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The activity of phenformin needs to be characterized in further detail in vitro as well as in vivo prior to upcoming clinical trials
Because both mitochondrial and cytosolic GSTs exist as dimers, and only heterodimers form between members of the same class, the second subfamily component of the enzyme dimer is denoted with a hyphen, followed by an additional Arabic numeral
Still, larger studies are needed to confirm the safety of L-carnitine during pregnancy
In this context, we also demonstrated that the disruption of the cellular redox buffer, controlled by GSH, increases not only the oxidative stress (Filomeni et al., 2005a), but also the endogenous physiological flux of NO in neuronal cells ( S -nitrosylation, and DNA strand breaks in neuronal cells
Differential and overlapping effects of 20,23(OH)2D3 and 1,25(OH)2D3 on gene expression in human epidermal keratinocytes: identification of AhR as an alternative receptor for 20,23(OH)2D3
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